Transcriptomics

Dataset Information

29

SW480 Signaling Hub Inhibition


ABSTRACT: In tumor cells, stepwise oncogenic deregulation of signaling cascades induces alterations of cellular morphology and promotes the acquisition of malignant traits. Using a panel of small molecular inhibitors, we established associated gene expression signatures of key signaling hubs. SW480 cells were grown in DMEM, 10% FCS, and treated for 24h with the following inhibitors or with solvent (DMSO): SU5402 (42uM); U0126 (10uM), SP600125 (20uM), LY294002 (20uM)

ORGANISM(S): Homo sapiens  

SUBMITTER: M Leushacke  Markus Morkel   M Morkel    

PROVIDER: E-GEOD-29689 | ArrayExpress| 2011-06-17

SECONDARY ACCESSION(S): GSE29689PRJNA141107

REPOSITORIES: GEO, ArrayExpress

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