Ontology highlight
ABSTRACT:
ORGANISM(S): Homo sapiens
SUBMITTER: Hendrik J de Jonge Andre Mulder Annet Z Vos Carolien M Woolthuis Edo Vellenga Jan J Schuringa Gerwin Huls JJ Schuringa Karen van der Weide Eveline S de Bont Philip M Kluin Eva van den Berg
PROVIDER: E-GEOD-30029 | ArrayExpress | 2011-07-18
SECONDARY ACCESSION(S): GSE30029PRJNA144051
REPOSITORIES: GEO, ArrayExpress
de Jonge H J M HJ Woolthuis C M CM Vos A Z AZ Mulder A A van den Berg E E Kluin P M PM van der Weide K K de Bont E S J M ES Huls G G Vellenga E E Schuringa J J JJ
Leukemia 20110715 12
In order to identify acute myeloid leukemia (AML) CD34(+)-specific gene expression profiles, mononuclear cells from AML patients (n=46) were sorted into CD34(+) and CD34(-) subfractions, and genome-wide expression analysis was performed using Illumina BeadChip Arrays. AML CD34(+) and CD34(-) gene expression was compared with a large group of normal CD34(+) bone marrow (BM) cells (n=31). Unsupervised hierarchical clustering analysis showed that CD34(+) AML samples belonged to a distinct cluster c ...[more]