Ontology highlight
ABSTRACT:
OTHER RELATED OMICS DATASETS IN: PRJNA130441PRJNA143371PRJNA130905PRJNA136037PRJNA140285
ORGANISM(S): Homo Sapiens
SUBMITTER: Guoliang Li Edison T Liu Say L Kong
PROVIDER: E-GEOD-30574 | ArrayExpress | 2011-09-04
SECONDARY ACCESSION(S): GSE30574PRJNA143371
REPOSITORIES: GEO, ArrayExpress
Action | DRS | |||
---|---|---|---|---|
E-GEOD-30574.README.txt | Txt | |||
E-GEOD-30574.idf.txt | Idf | |||
E-GEOD-30574.processed.1.zip | Processed | |||
E-GEOD-30574.sdrf.txt | Txt |
Items per page: 1 - 4 of 4 |
Molecular systems biology 20110830
Despite the role of the estrogen receptor α (ERα) pathway as a key growth driver for breast cells, the phenotypic consequence of exogenous introduction of ERα into ERα-negative cells paradoxically has been growth inhibition. We mapped the binding profiles of ERα and its interacting transcription factors (TFs), FOXA1 and GATA3 in MCF-7 breast carcinoma cells, and observed that these three TFs form a functional enhanceosome that regulates the genes driving core ERα function and cooperatively modul ...[more]