Transcriptomics

Dataset Information

4

Cis-Expression QTL Analysis of Established Risk Variants for Colorectal Cancer


ABSTRACT: Genome-wide association studies (GWAS) have identified 19 risk variants associated with colorectal cancer. As most of these risk variants reside outside the coding regions of genes, we conducted cis-expression quantitative trait loci (cis-eQTL) analyses to investigate possible regulatory functions on the expression of neighboring genes. Forty microsatellite stable and CpG island methylator phenotype-negative colorectal tumors and paired adjacent-normal colon tissues were used for genome-wide SNP and gene expression profiling in our cis-eQTL analyses. This submission represents transcriptome component of study.

ORGANISM(S): Homo sapiens  

SUBMITTER: James M Church   Iona Cheng  David J Duggan  Lenora W Loo  Lucas M Dunklee  Graham Casey  Steven Gallinger  Maarit Tiirikainen  Daniel J Weisenberger  Robert Gryfe  Robert W Haile  Ann Seifried  Lenora WM Loo  Loic L Marchand  Stephen N Thibodeau  Annette Lum-Jones 

PROVIDER: E-GEOD-31737 | ArrayExpress | 2012-01-31

SECONDARY ACCESSION(S): GSE31737PRJNA145435

REPOSITORIES: GEO, ArrayExpress

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