Ontology highlight
ABSTRACT:
ORGANISM(S): Homo sapiens
SUBMITTER: yuriko saiki Akira Horii Yuriko Saiki Takenori Ogawa
PROVIDER: E-GEOD-32176 | ArrayExpress | 2012-06-13
SECONDARY ACCESSION(S): GSE32176PRJNA147413
REPOSITORIES: GEO, ArrayExpress
Cancer science 20120706 9
For the purpose of analyzing mechanisms related to the cis-diamminedichloroplatinum resistance in head and neck squamous cell carcinoma, we analyzed RPMI2650 and its derived previously established cis-diamminedichloroplatinum resistant cell line RPMI2650CR. To identify resistant phenotype-related microRNAs, we compared microRNA expressions between RPMI2650CR and RPMI2650 by microarray. One of the microRNAs as downregulated, miR-34a, was further investigated. Decreased expression of miR-34a in RP ...[more]