Transcriptomics

Dataset Information

4

Ssa1/2 deletion mutant


ABSTRACT: Yeast strain lacking the two genes SSA1 and SSA2, which encode cytosolic chaperones, acquires thermotolerance as well as the mild heat-shocked wild-type yeast strain. Series containes 3 independent experiments.

ORGANISM(S): Saccharomyces cerevisiae  

SUBMITTER: Hitoshi Iwahashi   Kuniko Akama  Rena Matsumoto  Randeep Rakwal 

PROVIDER: E-GEOD-3315 | ArrayExpress | 2010-06-30

SECONDARY ACCESSION(S): GSE3315PRJNA93349

REPOSITORIES: GEO, ArrayExpress

Dataset's files

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E-GEOD-3315.README.txt Txt
E-GEOD-3315.idf.txt Idf
E-GEOD-3315.processed.1.zip Processed
E-GEOD-3315.sdrf.txt Txt
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Publications

The stress response against denatured proteins in the deletion of cytosolic chaperones SSA1/2 is different from heat-shock response in Saccharomyces cerevisiae.

Matsumoto Rena R   Akama Kuniko K   Rakwal Randeep R   Iwahashi Hitoshi H  

BMC genomics 20051007


<h4>Background</h4>A yeast strain lacking the two genes SSA1 and SSA2, which encode cytosolic molecular chaperones, acquires thermotolerance as well as the mild heat-shocked wild-type yeast strain. We investigated the genomic response at the level of mRNA expression to the deletion of SSA1/2 in comparison with the mild heat-shocked wild-type using cDNA microarray.<h4>Results</h4>Yeast cDNA microarray analysis revealed that genes involved in the stress response, including molecular chaperones, we  ...[more]

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