Dataset Information


Genomic characterization of the MPNST

ABSTRACT: Malignant peripheral nerve sheath tumor (MPNST) is a rare sarcoma that lacks effective therapeutic strategies. By characterizing recurrent gene copy number aberrations, we gain insight into the most altered pathways with the purpose of scanning possible therapeutic targets. We conducted a microarray-based comparative genomic hybridization profiling of two cohorts of primary MPNST tissue samples including 25 patients treated at The University of Texas MD Anderson Cancer Center and 26 patients from Tianjin Cancer Hospital. All samples had at least 90% tumor content. Commercially available normal genomic DNAs were used as control.

ORGANISM(S): Homo sapiens  

SUBMITTER: Antti Ylipää   Wei Zhang  Dina C Lev  Matti Nykter  Hong Zheng  Nancy Ratner  Jonathan Trent  Kexin Chen  Yan Sun  Jilong Yang 

PROVIDER: E-GEOD-33881 | ArrayExpress | 2011-11-26



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