Transcriptomics

Dataset Information

9

Transcriptomic analysis of Etoposide-treated 293 cells expressing p65 wt or p65 S547A


ABSTRACT: We reported a direct phosphorylation of the Ser547 of the RelA/p65 subunit of NF-kB by ATM kinase. A comparative transcriptomic analyse with HEK293 cells expressing exclusively HA-p65wt or a non-phosphorylable mutant HA-p65S547A was conducted to identify the genes regulated by this phosphorylation after an Etoposide treatment. HEK293 cells expressing exclusively HA-p65wt or HA-p65S547A were treated during four or eight hours with Etoposide or left untreated. This was performed three times to obtain independent triplicates for the microarray expermiment.

ORGANISM(S): Homo sapiens  

SUBMITTER: Frank Dequiedt   Yvette Habraken  Emmanuel Divalentin  Geoffrey Gloire  Jacques Piette  Helene Sabatel 

PROVIDER: E-GEOD-33990 | ArrayExpress | 2012-05-30

SECONDARY ACCESSION(S): GSE33990PRJNA150633

REPOSITORIES: GEO, ArrayExpress

Dataset's files

Source:
Action DRS
E-GEOD-33990.README.txt Txt
E-GEOD-33990.additional.1.zip Other
E-GEOD-33990.idf.txt Idf
E-GEOD-33990.processed.1.zip Processed
E-GEOD-33990.sdrf.txt Txt
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