Transcriptomics

Dataset Information

3

Metabolic features of Cryptosporidium parvum oocysts: Control vs. UV treatment.


ABSTRACT: Global gene expression in C. parvum environmental stage (oocysts) and the oocysts treated with UV comparing control untreated ones. Goal was to uncover the metabolic features in oocysts and the oocysts treated with UV. two-condition experiment, UV treatment vs. UV untreatment; two time points, 0.5h and 5h. Each time point, two Biological replicates(1, 2) with two technique replicates(1-1,1-2 ; 2-1, 2-2).

ORGANISM(S): Cryptosporidium parvum  

SUBMITTER: Guan Zhu   haili zhang  Haili Zhang  Fengguang Guo  Huaijun Zhou 

PROVIDER: E-GEOD-34307 | ArrayExpress | 2012-12-31

SECONDARY ACCESSION(S): GSE34307PRJNA151511

REPOSITORIES: GEO, ArrayExpress

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Publications

Transcriptome analysis reveals unique metabolic features in the Cryptosporidium parvum Oocysts associated with environmental survival and stresses.

Zhang Haili H   Guo Fengguang F   Zhou Huaijun H   Zhu Guan G  

BMC genomics 20121121


<h4>Background</h4>Cryptosporidium parvum is a globally distributed zoonotic parasite and an important opportunistic pathogen in immunocompromised patients. Little is known on the metabolic dynamics of the parasite, and study is hampered by the lack of molecular and genetic tools. Here we report the development of the first Agilent microarray for C. parvum (CpArray15K) that covers all predicted ORFs in the parasite genome. Global transcriptome analysis using CpArray15K coupled with real-time qRT  ...[more]

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