Transcriptomics

Dataset Information

4

Global gene expression divergence among mutation-accumulation Y-chromosome substitution lines of Drosophila melanogaster


ABSTRACT: Gene expression profiling revealed that hundreds of genes were differentially expressed among these Y introgression lines, and that global gene expression pattern diverged between the low-PEV and high-PEV (defined in the accompanying publication) flies. The results further expand our understanding of the role of the Y chromosome in modulating global gene expression, and suggest a link with modifications of chromatin state. Keywords: position-effect variegation (PEV) The Y chromosomes of H15 and H23 have lower level of suppression on the expression of white gene, therefore show lower level of eye color variegation. In contrast, the Y chromosomes of H5 and H7 have higher level of suppression on the expression of white gene resulting higher level of eye variegation. A loop design was used with all the Y introgression lines. In addition to biological replicates, a Cy5-Cy3 dye swap was performed.

ORGANISM(S): Drosophila melanogaster  

SUBMITTER: Jun Zhou  

PROVIDER: E-GEOD-37068 | ArrayExpress | 2012-04-04

SECONDARY ACCESSION(S): GSE37068PRJNA157969

REPOSITORIES: GEO, ArrayExpress

Similar Datasets

2009-02-18 | GSE12395 | GEO
2013-02-15 | E-GEOD-44329 | ArrayExpress
2013-05-01 | E-GEOD-46313 | ArrayExpress
2011-09-29 | E-GEOD-31907 | ArrayExpress
2010-05-06 | E-GEOD-12191 | ArrayExpress
2010-05-08 | E-GEOD-21587 | ArrayExpress
2010-10-02 | E-GEOD-23612 | ArrayExpress
2012-01-31 | E-GEOD-35418 | ArrayExpress
2013-02-01 | E-GEOD-42157 | ArrayExpress
2014-08-19 | E-GEOD-60496 | ArrayExpress