Transcriptomics

Dataset Information

5

PGE2 promotes recovery from established Nephrotoxic Serum Nephritis in mice.


ABSTRACT: We induced acute nephritis by single injection of sheep nephrotoxic serum in mice and then treated the mice with prostaglandin E2. We used microarrays to examine the global gene expressions during recovery from nephrotoxic nephritis by prostaglandin E2. Acute nephristis was induced in female mice by single injection of sheep Nephortoxc Serum (NTS), followed by prostaglandin E2 administration daily starting from day 2 after NTS administration. Mice were sacrificed on day 7 and RNAs were isolated from kidney. The RNA samples were subjected to mouse gene 1.0 ST array analysis.

ORGANISM(S): Mus musculus  

SUBMITTER: Michael P Madaio   Nino Kvirkvelia  Malgorzata McMenamin 

PROVIDER: E-GEOD-37402 | ArrayExpress | 2012-04-22

SECONDARY ACCESSION(S): GSE37402PRJNA159741

REPOSITORIES: GEO, ArrayExpress

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