Transcriptomics

Dataset Information

5

Effect of ATF4 overexpression on mRNA levels in differentiated C2C12 myotubes.


ABSTRACT: ATF4 is a bZIP transcription factor that that promotes skeletal muscle atrophy. The goal of these studies was to determine the effects of ATF4 overexpression on mRNA levels in differentiated C2C12 myotubes. For additional details see Ebert et al, Stress-Induced Skeletal Muscle Gadd45a Expression Reprograms Myonuclei and Causes Muscle Atrophy. JBC epub. June 12,2012 C2C12 myotubes were infected with adenovirus co-expressing eGFP and ATF4-FLAG. Control myotubes were infected with adenovirus co-expressing eGFP and a transcriptionally inactive ATF4 construct (ATF4∆bZIP).

REANALYSED by: E-GEOD-39194

ORGANISM(S): Mus musculus  

SUBMITTER: Christopher M Adams   Christopher Adams  Scott M Ebert 

PROVIDER: E-GEOD-39194 | ArrayExpress | 2012-09-15

SECONDARY ACCESSION(S): GSE39194PRJNA170207

REPOSITORIES: GEO, ArrayExpress

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