Transcriptomics

Dataset Information

356

Transcriptional Analysis of lsm1a lsm1b Arabidopsis mutant.


ABSTRACT: Characterization of the lsm1a lsm1b transcriptional profile. LSM1 protein is involved in RNA decay through decapping facilitation. The performed array help us to understand the transcription level alterations produced by the absence of LSM1. One-condition experiment, Col-0 vs. lsm1a lsm1b plants. Biological replicates: 3 control replicates.

ORGANISM(S): Arabidopsis thaliana  

SUBMITTER: Carlos Perea-Resa   Julio Salinas  Tamara Hernández-Verdeja 

PROVIDER: E-GEOD-39630 | ArrayExpress | 2013-01-16

SECONDARY ACCESSION(S): GSE39630PRJNA171301

REPOSITORIES: GEO, ArrayExpress

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Publications

LSM proteins provide accurate splicing and decay of selected transcripts to ensure normal Arabidopsis development.

Perea-Resa Carlos C   Hernández-Verdeja Tamara T   López-Cobollo Rosa R   del Mar Castellano María M   Salinas Julio J  

The Plant cell 20121207 12


In yeast and animals, SM-like (LSM) proteins typically exist as heptameric complexes and are involved in different aspects of RNA metabolism. Eight LSM proteins, LSM1 to 8, are highly conserved and form two distinct heteroheptameric complexes, LSM1-7 and LSM2-8,that function in mRNA decay and splicing, respectively. A search of the Arabidopsis thaliana genome identifies 11 genes encoding proteins related to the eight conserved LSMs, the genes encoding the putative LSM1, LSM3, and LSM6 proteins b  ...[more]

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