Dataset Information


SM019 - Infection with SARS MA15 of C57BL/6J mice and Tnfrsf1b knockout mice

ABSTRACT: Comparing the host response of C57BL/6J mice to Tnfrsf1b knockouts in the same strain of mice. Groups of 10-week-old C57BL/6 mice or Tnfrsf1a/1b knockout mice were infected with SARS MA15 at a dose of 10^5 PFU or mock infected. Mice were euthanized on days 4 and 7 post-infection to measure virus load and isolate samples for measurement of virus load, lung pathology, transcriptional analysis and proteomics analysis. Mock-infected animals were also harvested at each time point. Mice were weighed every 24 hours to measure general disease progression and any mouse approaching 30% weight loss was euthanized.

ORGANISM(S): Mus musculus  

SUBMITTER: Lynn Law  Ralph Baric   Jean Chang   Richard Roy Green   Michael Katze   Lisa Gralinski    

PROVIDER: E-GEOD-40824 | ArrayExpress | 2012-09-13



altmetric image


Sorry, this publication's infomation has not been loaded in the Indexer, please go directly to PUBMED or Altmetric.

Similar Datasets

2012-09-13 | E-GEOD-40840 | ArrayExpress
2012-09-12 | E-GEOD-40792 | ArrayExpress
2012-09-13 | E-GEOD-40827 | ArrayExpress
2012-02-20 | E-GEOD-35940 | ArrayExpress
2012-09-13 | E-GEOD-40844 | ArrayExpress
2012-05-13 | E-GEOD-37829 | ArrayExpress
2012-05-13 | E-GEOD-37951 | ArrayExpress
2014-08-20 | E-GEOD-50076 | ArrayExpress
2015-01-04 | E-GEOD-43309 | ArrayExpress
2012-02-21 | E-GEOD-35943 | ArrayExpress