Genomics

Dataset Information

299

Clustered regulatory signals at nucleosome-depleted regions punctuate a constant nucleosomal landscape in Schizosaccharomyces pombe


ABSTRACT: Sequencing of mononucleosomal DNA during asynchronous mitosis and 0, 3 and 5 hours into meiosis in Schizosaccharomyces pombe. Two samples from mononucleosomal DNA from asynchronous mitosis (haploid 972 h- and diploid pat1.114) and three samples from 0, 3 and 5 hours into meiosis (from diploid pat1.114) were sequenced (Illumina Genome Analyzer IIx) using the single-end read protocol.

ORGANISM(S): Schizosaccharomyces pombe  

SUBMITTER: Luis Quintales   Ignacio Soriano  Francisco Antequera 

PROVIDER: E-GEOD-41772 | ArrayExpress | 2013-11-25

SECONDARY ACCESSION(S): GSE41772SRP016592PRJNA178153

REPOSITORIES: GEO, ArrayExpress, ENA

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Publications

Clustered regulatory elements at nucleosome-depleted regions punctuate a constant nucleosomal landscape in Schizosaccharomyces pombe.

Soriano Ignacio I   Quintales Luis L   Antequera Francisco F  

BMC genomics 20131121


BACKGROUND: Nucleosomes facilitate the packaging of the eukaryotic genome and modulate the access of regulators to DNA. A detailed description of the nucleosomal organization under different transcriptional programmes is essential to understand their contribution to genomic regulation. RESULTS: To visualize the dynamics of individual nucleosomes under different transcriptional programmes we have generated high-resolution nucleosomal maps in Schizosaccharomyces pombe. We show that 98.5% of the ge  ...[more]

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