Dataset Information


Genome-wide transcriptional analysis of PE-2 strain of Saccharomyces cerevisiae

ABSTRACT: In this study we investigate the molecular physiology of the main S. cerevisiae commercial strain (PE-2) used on Brazilian bioethanol process under two distinct conditions: typical (TF) and flocculated (co-aggregated - FL) fermentation. Transcriptional machinery of PE-2 was assessed by high throughput sequencing-based methods (RNA-seq) during industrial fed-batch fermentations. Data from comparative analysis revealed distinct transcriptional profiles among conditions, characterized mainly by a deep gene repression on FL process. We investigated the transcriptional changes in S. cerevisiae PE-2 strain under industrial fermentation conditions using RNA-seq protocols. We analyzed 13 fermentation time-points where 6 time-points on typical fermentation conditions (TF) and 7 time-points on flocculate conditions(FL). The raw data have been submitted to SRA as SRP014755

ORGANISM(S): Saccharomyces cerevisiae  

SUBMITTER: Osmar V Carvalho-Netto   Osmar Netto  Juan L Argueso  Luige A Calderón  Paulo J Teixeira  Marcelo F Carazzolle  Gonçalo A Pereira  Luciana S Mofatto  Melline F Noronha  Piotr A Mieczkowski 

PROVIDER: E-GEOD-41834 | ArrayExpress | 2015-02-02



altmetric image


Saccharomyces cerevisiae transcriptional reprograming due to bacterial contamination during industrial scale bioethanol production.

Carvalho-Netto Osmar V OV   Carazzolle Marcelo F MF   Mofatto Luciana S LS   Teixeira Paulo J P L PJ   Noronha Melline F MF   Calderón Luige A L LA   Mieczkowski Piotr A PA   Argueso Juan Lucas JL   Pereira Gonçalo A G GA  

Microbial cell factories 20150130

The bioethanol production system used in Brazil is based on the fermentation of sucrose from sugarcane feedstock by highly adapted strains of the yeast Saccharomyces cerevisiae. Bacterial contaminants present in the distillery environment often produce yeast-bacteria cellular co-aggregation particles that resemble yeast-yeast cell adhesion (flocculation). The formation of such particles is undesirable because it slows the fermentation kinetics and reduces the overall bioethanol yield.In this stu  ...[more]

Similar Datasets

2015-12-09 | E-GEOD-75803 | ArrayExpress
2013-10-16 | E-GEOD-34117 | ArrayExpress
2011-02-11 | E-GEOD-26929 | ArrayExpress
2011-01-14 | E-GEOD-26618 | ArrayExpress
2011-01-19 | E-GEOD-26437 | ArrayExpress
2011-01-14 | E-GEOD-26617 | ArrayExpress
2008-07-01 | GSE11651 | GEO
2008-10-21 | E-GEOD-11651 | ArrayExpress
2008-06-16 | E-GEOD-9423 | ArrayExpress
2011-02-28 | E-GEOD-26965 | ArrayExpress