Transcriptomics

Dataset Information

3

Gene expression analysis of human CD4+ T cells differentiated into Th17 cells in the presence of high-salt


ABSTRACT: Th17 cells are believed to be a critical cell population for driving autoimmune diseases. However, environmental factors that are directly related to the development of Th17 cells are largely unknown. High-salt (NaCl) concentrations enhance Th17 differentiation of human naive CD4+ T cells in vitro. The aim of the study was to analyse the changes in gene expression induced by high-salt conditions during Th17 differentiation. Naive human CD4+ T cells were in vitro differentiated into Th17 cells in the presence or absence of high-salt. We arrayed 2 different donors for each condition (control & high-salt).

ORGANISM(S): Homo sapiens  

SUBMITTER: Dominik N Muller   David A Hafler  Nir Yosef  Markus Kleinewietfeld  Arndt Manzel  Ralf A Linker 

PROVIDER: E-GEOD-42569 | ArrayExpress | 2013-03-07

SECONDARY ACCESSION(S): GSE42569PRJNA182290

REPOSITORIES: GEO, ArrayExpress

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