Transcriptomics

Dataset Information

5

IM006A - Mouse infection with PB1-F2del: A/Vietnam/1203-CIP048_RG3/2004 (H5N1) at 10^3 PFU


ABSTRACT: To determine the host response (C57BL/6 mouse model) to the PB1-F2del: A/Vietnam/1203-CIP048_RG3/2004 (H5N1) virus at 10^3 PFU. Groups of 20-week-old C57BL/6 mice were infected with the PB1-F2del: A/Vietnam/1203-CIP048_RG3/2004 (H5N1) virus at 10^3 PFU or time-matched mock infected. Time points were 1, 2, 4 and 7 d.p.i. There were 5 mice/time point for infections and 3 mice/time point for time-matched mocks. Lung samples were collected for virus load, transcriptional analysis and proteomics analysis. Weight loss and animal survival were also monitored.

ORGANISM(S): Mus musculus  

SUBMITTER: Yoshi Kawoaka   Amie Eisfeld  Lynn Law  Jean Chang  Richard Roy Green  Chengjun Li  Michael Katze 

PROVIDER: E-GEOD-43302 | ArrayExpress | 2013-01-19

SECONDARY ACCESSION(S): GSE43302PRJNA186877

REPOSITORIES: GEO, ArrayExpress

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