Transcriptomics

Dataset Information

4

Expression data of mammary epithelial cells during the epithelial-mesenchymal transition


ABSTRACT: The EMT program allows epithelial cells to become endowed with motility, invasiveness and stem cell traits. We investigated difference in signaling networks that are differentially utilized in EMTed and non-EMTed cells, thereby identifying therapeutic targets that are unique to EMT/cancer stem cells. We expressed the EMT transcription factors, Twist, Snail and Slug in HMLE human mammary epithelial cells, and compared their gene expression with parental cells. We identified kinases that are more differentially regulated between the epithelial and mesenchymal cell state.

ORGANISM(S): Homo sapiens  

SUBMITTER: Wai Leong Tam   Wai L Tam 

PROVIDER: E-GEOD-43495 | ArrayExpress | 2013-09-09

SECONDARY ACCESSION(S): GSE43495PRJNA186603

REPOSITORIES: GEO, ArrayExpress

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