Transcriptomics

Dataset Information

2

Expression data from D. melanogaster pupal wings


ABSTRACT: The goal of this gene expression profiling experiment was to identify the entire set of transcription factors expressed during late pupal wing development (~80h APF) when pigmentation genes are expressed We used Affymetrix microarrays to profile the expression of the transcription factors in late pupal wings of Oregon R flies. The staging of the flies was made by eye, based on the extent of wing pigmentation. RNA was extracted from batches of 40 flies and three biological replicates were analyzed.

ORGANISM(S): Drosophila melanogaster  

SUBMITTER: Benjamin Prud'homme   Benjamin Prudhomme 

PROVIDER: E-GEOD-43673 | ArrayExpress | 2013-02-01

SECONDARY ACCESSION(S): GSE43673PRJNA187044

REPOSITORIES: GEO, ArrayExpress

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Publications

Emergence and diversification of fly pigmentation through evolution of a gene regulatory module.

Arnoult Laurent L   Su Kathy F Y KF   Manoel Diogo D   Minervino Caroline C   Magriña Justine J   Gompel Nicolas N   Prud'homme Benjamin B  

Science (New York, N.Y.) 20130301 6126


The typical pattern of morphological evolution associated with the radiation of a group of related species is the emergence of a novel trait and its subsequent diversification. Yet the genetic mechanisms associated with these two evolutionary steps are poorly characterized. Here, we show that a spot of dark pigment on fly wings emerged from the assembly of a novel gene regulatory module in which a set of pigmentation genes evolved to respond to a common transcriptional regulator determining thei  ...[more]

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