Ontology highlight
ABSTRACT:
ORGANISM(S): Homo sapiens
SUBMITTER: Deepa Rastogi John Greally Masako Suzuki
PROVIDER: E-GEOD-43705 | ArrayExpress | 2014-04-14
SECONDARY ACCESSION(S): SRP018119GSE43705PRJNA187088
REPOSITORIES: GEO, ArrayExpress, ENA
Action | DRS | |||
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E-GEOD-43705.idf.txt | Idf | |||
E-GEOD-43705.processed.1.zip | Processed | |||
E-GEOD-43705.processed.2.zip | Processed | |||
E-GEOD-43705.sdrf.txt | Txt |
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Scientific reports 20130101
While DNA methylation plays a role in T-helper (Th) cell maturation, its potential dysregulation in the non-atopic Th1-polarized systemic inflammation observed in obesity-associated asthma is unknown. We studied DNA methylation epigenome-wide in peripheral blood mononuclear cells (PBMCs) from 8 obese asthmatic pre-adolescent children and compared it to methylation in PBMCs from 8 children with asthma alone, obesity alone and healthy controls. Differentially methylated loci implicated certain bio ...[more]