Transcriptomics

Dataset Information

3

Gene expression of pancreatic tumors


ABSTRACT: Solid-pseudopapillary neoplasm of pancreas(SPN), ductal adenocarcinoma(PCA), neuroendocrine tumor(NET) and non-neoplastic pancreas. To investigate the specific gene expression of SPN compared to other types of pancreatic tumor, we analyzed large-scale gene expressioin analysis to identify the molecular signature that may affect SPN tumorigenesis. Differentially expressed genes were analyzed on SPNs, PCAs, NETs and Non-neoplastic tissues. Solid-pseudopapillary neoplasm (SPN) is an uncommon pancreatic tumor with distinct clinicopathologic features. SPNs are characterized by mutations in exon 3 of CTNNB1. However, little is known about the gene and microRNA expression profiles of SPNs. Thus, we sought to characterize SPN-specific gene expression and identify the signaling pathways activated in these tumors. The mRNA expression profile of 14 SPNs, 6 pancreatic adenocarcinomas (PCAs), 6 pancreatic neuroendocrine tumors (NETs), and five non-neoplastic pancreatic tissues were analyzed.

ORGANISM(S): Homo sapiens  

SUBMITTER: Hoguen Kim   minhee park  Minhyung Kim  Minhee Park 

PROVIDER: E-GEOD-43795 | ArrayExpress | 2013-12-31

SECONDARY ACCESSION(S): GSE43795PRJNA187452

REPOSITORIES: GEO, ArrayExpress

Similar Datasets

2013-12-31 | E-GEOD-43796 | ArrayExpress
| GSE24358 | GEO
2010-12-23 | GSE19650 | GEO
2012-12-12 | E-GEOD-24358 | ArrayExpress
2010-12-23 | E-GEOD-19650 | ArrayExpress
| PRJNA187451 | ENA
| GSE21163 | GEO
2010-04-14 | E-GEOD-21163 | ArrayExpress
2013-01-08 | E-MTAB-388 | ArrayExpress
2015-08-07 | E-GEOD-19650 | ExpressionAtlas