Transcriptomics

Dataset Information

2

MiRNA analysis during hepatitis C virus infection


ABSTRACT: This study is complementary to the "Genome-wide analysis of host mRNA translation during hepatitis C virus infection" study (GSE44210), for which sucrose gradient ultracentrifugation followed by microarray analysis was used to identify translationally-regulated mRNAs (mRNAs associated with ribosomes) from JFH1-infected and uninfected Huh-7.5.1 cells. MicroRNA arrays have been conducted in parallel on total RNA from infected and uninfected cells, in order to determine if microRNA regulation could explain some of the mRNA translation regulations. Huh7 cells were infected with HCV JFH-1 strain. Controls consisted in non-infected cells. 3 days after infection, total RNAs were extracted from cell lysate and subjected to miRNA microarray analysis.

ORGANISM(S): Homo sapiens  

SUBMITTER: Sandra Pierredon   Catherine Le Berre-Scoul  Cyrille Féray  Helene Colman  Céline Hernandez  Audrey Bihouée  Stephan Vagner  Arielle R Rosenberg  Rémi Houlgatte  Hélène Colman 

PROVIDER: E-GEOD-44369 | ArrayExpress | 2013-02-17

SECONDARY ACCESSION(S): GSE44369PRJNA189657

REPOSITORIES: GEO, ArrayExpress

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