Ontology highlight
ABSTRACT:
ORGANISM(S): Mus musculus
SUBMITTER: J M Boss Chris Scharer C D Scharer
PROVIDER: E-GEOD-44638 | ArrayExpress | 2013-08-18
SECONDARY ACCESSION(S): SRP018844GSE44638PRJNA191093
REPOSITORIES: GEO, ArrayExpress, ENA
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E-GEOD-44638.additional.1.zip | Other | |||
E-GEOD-44638.idf.txt | Idf | |||
E-GEOD-44638.processed.1.zip | Processed | |||
E-GEOD-44638.processed.2.zip | Processed | |||
E-GEOD-44638.processed.3.zip | Processed |
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Journal of immunology (Baltimore, Md. : 1950) 20130816 6
The differentiation of CD8 T cells in response to acute infection results in the acquisition of hallmark phenotypic effector functions; however, the epigenetic mechanisms that program this differentiation process on a genome-wide scale are largely unknown. In this article, we report the DNA methylomes of Ag-specific naive and day-8 effector CD8 T cells following acute lymphocytic choriomeningitis virus infection. During effector CD8 T cell differentiation, DNA methylation was remodeled such that ...[more]