Transcriptomics

Dataset Information

8

Defining a Th9 transcriptome


ABSTRACT: Microarray analyses were performed to compare gene expression in cultured mouse Th9, Th2 and Treg cells and resting versus activated Th9 cells. Three replicates were analyzed for each culture condition; Th9 unstim, Th2 unstim, Treg unstim, Th9 stim

ORGANISM(S): Mus musculus  

SUBMITTER: Mark H Kaplan   M Kaplan 

PROVIDER: E-GEOD-44937 | ArrayExpress | 2014-03-26

SECONDARY ACCESSION(S): GSE44937PRJNA192560

REPOSITORIES: GEO, ArrayExpress

altmetric image

Publications


T helper 9 (Th9) cells are specialized for the production of IL-9, promote allergic inflammation in mice, and are associated with allergic disease in humans. It has not been determined whether Th9 cells express a characteristic transcriptional signature. In this study, we performed microarray analysis to identify genes enriched in Th9 cells compared with other Th subsets. This analysis defined a transcriptional regulatory network required for the expression of a subset of Th9-enriched genes. The  ...[more]

Similar Datasets

2012-03-17 | E-GEOD-36554 | ArrayExpress
2014-02-13 | E-GEOD-54938 | ArrayExpress
2014-02-20 | E-GEOD-41317 | ArrayExpress
2012-10-29 | E-TABM-1187 | ArrayExpress
2014-05-23 | E-GEOD-54697 | ArrayExpress
2016-06-14 | E-GEOD-79607 | ArrayExpress
2015-04-12 | E-GEOD-66944 | ArrayExpress
2013-12-31 | E-GEOD-51344 | ArrayExpress
2011-03-01 | E-GEOD-23719 | ArrayExpress
2009-06-06 | E-MEXP-2153 | ArrayExpress