Transcriptomics

Dataset Information

3

Human esophageal dysplasia (16 cases) vs. esophageal squamous cell carcinoma (59 cases)


ABSTRACT: Our aim is to identify frequent genomic aberrations both in ESCC and esophageal dysplasia, and to discover important copy number-driving genes and microRNAs in ESCC. We carried out array-based comparative genomic hybridization (array CGH) on 59 ESCC resection samples and 16 dysplasia biopsy samples. Expression of genes at 11q13.3 was analyzed by real-time PCR and immunohistochemistry (IHC). Integrated analysis was performed to identify genes or microRNAs with copy number-expression correlations. Two group experiment, esophageal dysplasia vs. esophageal squamous cell carcinoma. Biological replicates: 16 dysplasias vs. 59 carcinomas

ORGANISM(S): Homo sapiens  

SUBMITTER: Zhi-Zhou Shi   Ming-Rong Wang 

PROVIDER: E-GEOD-46452 | ArrayExpress | 2013-04-29

SECONDARY ACCESSION(S): GSE46452PRJNA200559

REPOSITORIES: GEO, ArrayExpress

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