Genomics

Dataset Information

0

Genome-wide parent-of-origin DNA methylation analysis [Methyl-seq]


ABSTRACT: Genomic imprinting is a form of epigenetic regulation that results in expression of either the maternally or paternally inherited allele of a subset of genes. Imprinted loci contain differentially methylated regions (DMRs) where cytosine methylation marks one of the parental alleles, providing cis-acting regulatory elements that influence the allelic expression of surrounding genes, however to date the total number of imprinted loci within the human genome is unknown. To characterize known imprinted DMRS and identify novel imprinted loci we have performed whole-genome bisulphite sequencing and high-resolution DNA methylation array analysis of healthy tissues. Sequencing of bisulfite converted DNA analysis of normal brain (white matter), liver and term placenta tissue

ORGANISM(S): Homo sapiens  

SUBMITTER: Manel Esteller   David Monk  Antonio Gómez 

PROVIDER: E-GEOD-46698 | ArrayExpress | 2013-12-28

SECONDARY ACCESSION(S): SRP022149GSE46698PRJNA201856

REPOSITORIES: GEO, ArrayExpress, ENA

Similar Datasets

2013-12-28 | E-GEOD-52578 | ArrayExpress
2014-08-12 | E-GEOD-46327 | ArrayExpress
2014-09-03 | E-GEOD-56763 | ArrayExpress
2016-01-08 | E-GEOD-52271 | ArrayExpress
2014-08-14 | E-GEOD-43697 | ArrayExpress
2014-08-14 | E-GEOD-48527 | ArrayExpress
2012-05-16 | E-GEOD-30344 | ArrayExpress
2013-12-28 | E-GEOD-52576 | ArrayExpress
2016-06-01 | E-GEOD-64244 | ArrayExpress
2013-06-12 | E-GEOD-47088 | ArrayExpress