Genomics

Dataset Information

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H3K27me3 is maintained at a reduced level in Suz12(Bgal/Bgal) ESCs [ChIP-Seq]


ABSTRACT: Suz12(Bgal/Bgal) ESCs express a truncated form of Suz12 fused to Beta-galactosidase. These cells maintain a reduced level of H3K27me3 despite this mutation to a core component of PRC2, unlike Eed-/- ESCs whose H3K27me3 is ablated. Two ESC lines mutant in genes of core components of Polycomb Repressive Complex 2 were assessed for H3K27me3 by ChIP-seq, as compared to a wild type ESC line.

ORGANISM(S): Mus musculus  

SUBMITTER: Seraphim R Thornton   Laurie A Boyer 

PROVIDER: E-GEOD-47483 | ArrayExpress | 2013-07-22

SECONDARY ACCESSION(S): SRP023268GSE47483PRJNA205856

REPOSITORIES: GEO, ArrayExpress, ENA

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