Transcriptomics

Dataset Information

7

Gene expression profiles MCF-10A cells overexpressing MBD2


ABSTRACT: Methylated DNA binding protein 2 (MBD2) has been shown to bind specific methylated promoters and suppress transcription. Here we systematically investigate MBD2 suppression by overexpressing MBD2 in MCF-10A cells and generating gene expression profiles of overexpressing cells and normal MCF-10A cells. MCF-10A cells were infected with MBD2 lentivirus in order to increase MBD2 expression. Total RNA was extracted from both infected and non-infected cells and hybridized to Affymetrix gene expression microarrays. Three technical replicates were hybridized for infected and non-infected cells.

ORGANISM(S): Homo sapiens  

SUBMITTER: Moshe Szyf   Johanne Wyglinski  Stephen Andrews  Matthew Suderman  Sebastian Alvarado 

PROVIDER: E-GEOD-47873 | ArrayExpress | 2013-06-17

SECONDARY ACCESSION(S): GSE47873PRJNA208362

REPOSITORIES: GEO, ArrayExpress

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