Dataset Information


Temperature-dependent alternative splicing of FLM controls flowering in Arabidopsis thaliana

ABSTRACT: How plants control the transition to flowering in response to ambient temperature is only beginning to be understood. In Arabidopsis thaliana, the MADS-box transcription factor genes FLOWERING LOCUS M (FLM) and SHORT VEGETATIVE PHASE (SVP) have key roles in this process. FLM is subject to temperature-dependent alternative splicing, producing two splice variants, FLM-β and FLM-δ, which compete for interaction with the floral repressor SVP. The SVP/FLM-β complex is predominately formed at low temperatures and prevents precocious flowering. In contrast, the competing SVP FLM-δ complex is impaired in DNA binding and acts as a dominant negative activator of flowering at higher temperatures. Our results demonstrate the importance of temperature-dependent alternative splicing in modulating the timing of the floral transition in response to environmental change. ChIP-seq A. thaliana FLM (3 replicates for gFLM and 2 replicates for FLM splice variants)

ORGANISM(S): Arabidopsis thaliana  

SUBMITTER: Johannes Mathieu   Levi Yant  Richard G Immink  David Posé  Markus Schmid  Leonie Verhage  Gerco C Angenent  Felix Ott 

PROVIDER: E-GEOD-48082 | ArrayExpress | 2013-09-19



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Temperature-dependent regulation of flowering by antagonistic FLM variants.

Posé David D   Verhage Leonie L   Ott Felix F   Yant Levi L   Mathieu Johannes J   Angenent Gerco C GC   Immink Richard G H RG   Schmid Markus M  

Nature 20130925 7476

The appropriate timing of flowering is crucial for plant reproductive success. It is therefore not surprising that intricate genetic networks have evolved to perceive and integrate both endogenous and environmental signals, such as carbohydrate and hormonal status, photoperiod and temperature. In contrast to our detailed understanding of the vernalization pathway, little is known about how flowering time is controlled in response to changes in the ambient growth temperature. In Arabidopsis thali  ...[more]

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