Transcriptomics

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KBM7 genetrap mutant cells stimulated with TNF-alpha and IFN-gamma


ABSTRACT: Transcriptional response of KBM7 cells to IFN-gamma or TNF-alpha was investigated in control or cells with genetrap insertions in JAK2 or TNFRS1A, respectively. The experiment shows that, as expected, cells lacking JAK2 or TNFRS1A expression display a severly blunted response to the tested cytokines. KBM7 genetrap mutant cells stimulated with TNF-alpha and IFN-gamma Sample WT_1 corresponds with the control sample for the IFN-gamma stimulation; Sample WT_2 corresponds with the control sample for the TNF-alpha stimulation. As the expected differences between the samples was large, only single replicates were performed for each condition

ORGANISM(S): Homo sapiens  

SUBMITTER: Sebastian Nijman   Sebastian M Nijman  Tilmann Buerckstuemmer 

PROVIDER: E-GEOD-48848 | ArrayExpress | 2013-08-09

SECONDARY ACCESSION(S): GSE48848PRJNA211962

REPOSITORIES: GEO, ArrayExpress

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