Transcriptomics

Dataset Information

2

Osteoblastic response in human bone marrow stromal cells


ABSTRACT: Our goal was to determine whether osteoblastic LuCaP 23.1 prostate cancer xenograft tumors can elicit an osteoblastic response at the gene expression level in human bone marrow stromal cells. Custom Agilent 44K whole human genome expression oligonucleotide microarrays were used to profile bone marrow stroma cells isolated from three patients and treated with either mineralization media or LuCaP 23.1 conditioned medium. Total RNA was isolated and amplified prior to hybridization against a common reference pool of prostate tumor cell lines.

ORGANISM(S): Homo sapiens  

SUBMITTER: Jessica Chin   Celestia Higano  Ilsa Coleman  Ruth Dumpit  Lawrence D True  Lisha Brown  Robert L Vessella  Eva Corey  Martin Tenniswood  Colm Morrissey  Bryce Lakely  Xiaotun Zhang  Sandy Larson  Paul H Lange  Peter S Nelson  Gregory J Mize 

PROVIDER: E-GEOD-48907 | ArrayExpress | 2013-12-23

SECONDARY ACCESSION(S): GSE48907PRJNA212244

REPOSITORIES: GEO, ArrayExpress

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