Dataset Information


Gene expression profile of ATF6a and ATF6b overexpression in LS174T cells

ABSTRACT: To further development of our mRNA expression approach to ER stress, we have employed whole genome microarray expression profiling as a discovery platform to identify ER stress-responsible genes. LS174T cells were overexpressed with ER stress mediators, ATF6a or ATF6b. Genes responsible for each mediator were extracted and categorized by Gene Ontology. ATF6a and ATF6b were overexpressed in LS174T. Subsequently, cells were treated with 2 mM sodium butyrate, which induces LS174T cells to differentiate to mature goblet cells. Genes responsible for each mediator were extracted and categorized by Gene Ontology in GeneRanker program of Genomatix platform.

ORGANISM(S): Homo sapiens  

SUBMITTER: Kazuna Takahara  Miho Oyadomari   Taiji Ito   Kazutoshi Mori   Seiko Kagawa   Mari Funahashi   Chinobu Miyamoto   Robert Zeng   Masato Miyake   Seiichi Oyadomari   Tomoko Mori   Eiji Tanaka    

PROVIDER: E-GEOD-49567 | ArrayExpress | 2015-08-05



altmetric image


Sorry, this publication's infomation has not been loaded in the Indexer, please go directly to PUBMED or Altmetric.

Similar Datasets

2015-01-18 | E-GEOD-35173 | ArrayExpress
2015-02-08 | E-GEOD-35651 | ArrayExpress
2015-01-18 | E-GEOD-35176 | ArrayExpress
2015-01-18 | E-GEOD-35175 | ArrayExpress
2015-01-18 | E-GEOD-35177 | ArrayExpress
2015-01-18 | E-GEOD-35174 | ArrayExpress
2014-10-22 | E-MTAB-1890 | ArrayExpress
2011-11-29 | E-GEOD-18560 | ArrayExpress
2013-02-20 | E-GEOD-37174 | ArrayExpress
2012-01-07 | E-GEOD-34926 | ArrayExpress