Transcriptomics

Dataset Information

3

Effect of Twist-box mutation on gene expression induced by Twist1 overexpression


ABSTRACT: Twist1 is a transcription factor that induces EMT and drives metastasis in prostate cancer. We examined global gene expression in Myc-CaP mouse prostate cancer cells following overexpression of Twist1 and the Twist1 mutants F191G, AQA, and DQD. 15 total samples were analysed, with 3 replicates of 5 groups: Twist1-WT, Twist1-AQA, Twist1-DQD, Twist1-F191G, and vector control. We performed the comparisons: WT > VEC, F191G > VEC. Samples were normalized by Twist1 expression in addition to normal

ORGANISM(S): Mus musculus  

SUBMITTER: R Gajula   Russell Williams  P Tran 

PROVIDER: E-GEOD-50002 | ArrayExpress | 2013-08-20

SECONDARY ACCESSION(S): GSE50002PRJNA215782

REPOSITORIES: GEO, ArrayExpress

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