Transcriptomics

Dataset Information

3

CSE-induced hydorogen sulfide improves glucose homeostasis and inhibits beta-cell failure in high-fat diet mice


ABSTRACT: CSE knockout (CSE-KO)mice at age 6 months were fed a high fat diet (HFD) for 8 weeks.we determined the effects of CSE knockdown on beta-cell function and mass in islets from the mice. After 8 weeks of the HFD,blood glucose levels were drasically increaced in CSE-KO mice compared with WT mice. To assess the effect of HFD on gene expression in CSE-KO mice,we performed a comparative DNA microarray analysis 2 samples analysis.control is CSE-WT(HFD+)

ORGANISM(S): Mus musculus  

SUBMITTER: Shigeki Taniguchi   Tomomi Ando  Mami Yamaoka  Toshihide Kimura  Masahiro Takei  Toshimasa Ishizaki  Isao Ishii  Mitsuhiro Okamoto  Kazuo Tohya  Ichiro Niki 

PROVIDER: E-GEOD-50458 | ArrayExpress | 2013-09-02

SECONDARY ACCESSION(S): GSE50458PRJNA217517

REPOSITORIES: GEO, ArrayExpress

Similar Datasets

2015-07-09 | E-GEOD-68202 | ArrayExpress
2014-06-06 | E-GEOD-57799 | ArrayExpress
2014-04-01 | E-GEOD-53444 | ArrayExpress
2014-06-30 | E-GEOD-54672 | ArrayExpress
2015-08-01 | E-GEOD-55443 | ArrayExpress
2016-08-01 | E-GEOD-76959 | ArrayExpress
2015-04-01 | E-GEOD-64715 | ArrayExpress
2014-08-23 | E-GEOD-60662 | ArrayExpress
2014-08-18 | E-GEOD-47797 | ArrayExpress
2016-07-26 | E-GEOD-68011 | ArrayExpress