Transcriptomics

Dataset Information

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Hemin and iron transcriptome of Porphyromonas gingivalis (part 1)


ABSTRACT: Transcriptional profiling of P. gingivalis cells comparing cells grown under hemin replete conditions to that grown under hemin depleted conditions Two-condition experiment, hemin replete vs. hemin deplete grown cells. Biological replicates: 3 independently grown and harvested bacterial cells. Four technical replicates (four replicates per array).

ORGANISM(S): Porphyromonas gingivalis  

SUBMITTER: Janina P Lewis   

PROVIDER: E-GEOD-50701 | ArrayExpress | 2015-05-18

SECONDARY ACCESSION(S): GSE50701PRJNA218626

REPOSITORIES: GEO, ArrayExpress

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Publications

Iron- and hemin-dependent gene expression of Porphyromonas gingivalis.

Anaya-Bergman C C   Rosato A A   Lewis J P JP  

Molecular oral microbiology 20140912 1


Although iron under anaerobic conditions is more accessible and highly reactive because of its reduced form, iron-dependent regulation is not well known in anaerobic bacteria. Here, we investigated iron- and hemin-dependent gene regulation in Porphyromonas gingivalis, an established periodontopathogen that primarily inhabits anaerobic pockets. Whole-genome microarrays of P. gingivalis genes were used to compare the levels of gene expression under iron-replete and iron-depleted conditions as well  ...[more]

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