Transcriptomics

Dataset Information

24

Gene expression profiling of non-invasion and invasion NFPAs


ABSTRACT: The application of gene expression profiling is to investigate the pathogenesis of aggressive NFPAs. And to identify biomarkers that could play a key role in aggressive behaviour of NFPAs Gene expression was measured among pituitary glands, non-invasion NFPAs and invasion NFPAs

ORGANISM(S): Homo sapiens  

SUBMITTER: Jie Feng   JIE FENG  Ya Z Zhang  Li Q Hong 

PROVIDER: E-GEOD-51618 | ArrayExpress | 2013-12-01

SECONDARY ACCESSION(S): GSE51618PRJNA224111

REPOSITORIES: GEO, ArrayExpress

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Publications

Identification of differentially expressed genes in pituitary adenomas by integrating analysis of microarray data.

Zhao Peng P   Hu Wei W   Wang Hongyun H   Yu Shengyuan S   Li Chuzhong C   Bai Jiwei J   Gui Songbai S   Zhang Yazhuo Y  

International Journal of Endocrinology 20150106


Pituitary adenomas, monoclonal in origin, are the most common intracranial neoplasms. Altered gene expression as well as somatic mutations is detected frequently in pituitary adenomas. The purpose of this study was to detect differentially expressed genes (DEGs) and biological processes during tumor formation of pituitary adenomas. We performed an integrated analysis of publicly available GEO datasets of pituitary adenomas to identify DEGs between pituitary adenomas and normal control (NC) tissu  ...[more]

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