Ontology highlight
ABSTRACT:
OTHER RELATED OMICS DATASETS IN: PRJNA224584PRJNA150983PRJNA224585PRJNA122965PRJNA144797PRJNA152559PRJNA224586
ORGANISM(S): Homo sapiens
DISEASE(S): Gastric Cancer
SUBMITTER: Na-Yu Chia Patrick Tan Niantao Deng
PROVIDER: E-GEOD-51704 | ArrayExpress | 2014-09-05
SECONDARY ACCESSION(S): GSE51704PRJNA224586
REPOSITORIES: GEO, ArrayExpress
Action | DRS | |||
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E-GEOD-51704.idf.txt | Idf | |||
E-GEOD-51704.processed.1.zip | Processed | |||
E-GEOD-51704.raw.1.zip | Raw | |||
E-GEOD-51704.sdrf.txt | Txt |
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Chia Na-Yu NY Deng Niantao N Das Kakoli K Huang Dachuan D Hu Longyu L Zhu Yansong Y Lim Kiat Hon KH Lee Ming-Hui MH Wu Jeanie J Sam Xin Xiu XX Tan Gek San GS Wan Wei Keat WK Yu Willie W Gan Anna A Tan Angie Lay Keng AL Tay Su-Ting ST Soo Khee Chee KC Wong Wai Keong WK Dominguez Lourdes Trinidad M LT Ng Huck-Hui HH Rozen Steve S Goh Liang-Kee LK Teh Bin-Tean BT Tan Patrick P
Gut 20140722 5
<h4>Objective</h4>Gastric cancer (GC) is a deadly malignancy for which new therapeutic strategies are needed. Three transcription factors, KLF5, GATA4 and GATA6, have been previously reported to exhibit genomic amplification in GC. We sought to validate these findings, investigate how these factors function to promote GC, and identify potential treatment strategies for GCs harbouring these amplifications.<h4>Design</h4>KLF5, GATA4 and GATA6 copy number and gene expression was examined in multipl ...[more]