Transcriptomics

Dataset Information

3

Chip-chip from HepG2 cells with EZH2, SUZ12 and H3K27me3


ABSTRACT: Polycomb group (PcG) proteins including EZH2, SUZ12 and so on, which specifically catalyze trimethylation of histone 3 lysine 27 (H3K27me3), and methylated H3K27 can be recognized by other specific binding proteins to compress chromatin structure, leading to the transcriptional repression of the target genes. To completely understand the epigenetic profile and molecular network of PcG in HCC, we performed ChIP-on-chip screens with EZH2, SUZ12 and H3K27me3 antibodies in HepG2 cells. Comparison of ChIP-on-chip results from EZH2, SUZ12 and H3K27me3.

ORGANISM(S): Homo sapiens  

SUBMITTER: Shu-bin Gao   Bin Xu  Shubin Gao 

PROVIDER: E-GEOD-52300 | ArrayExpress | 2013-11-13

SECONDARY ACCESSION(S): GSE52300PRJNA227365

REPOSITORIES: GEO, ArrayExpress

Dataset's files

Source:
Action DRS
E-GEOD-52300.additional.1.zip Other
E-GEOD-52300.idf.txt Idf
E-GEOD-52300.processed.1.zip Processed
E-GEOD-52300.raw.1.zip Raw
E-GEOD-52300.sdrf.txt Txt
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