Transcriptomics

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Comparative transcriptome analysis of Ptf1aCre;Kras,Brg1-/- vs. Ptf1a;Kras;p53+/- subcutaneous pancreatic ductal adenocarcinoma


ABSTRACT: In this experiment the RNA of s.c. grown tumors of cancer cell lines of murine Ptf1aCre;Kras,Brg1-/- vs. Ptf1a;Kras;p53+/- PDA was isolated and analyzed for gene expression. Ptf1aCre;Kras,Brg1-/- s.c. PDA grows more benign as compared to Ptf1a;Kras;p53+/- PDA; and the rationale of this study was to identify genes responsible for this different biological behavior. Total RNA of s.c. tumors of Ptf1aCre;Kras,Brg1-/- vs. Ptf1a;Kras;p53+/- cancer cell lines was isolated, purified and analyzed on the deep sequencing platform.

ORGANISM(S): Mus musculus  

SUBMITTER: Hertel Klemens   Nilotpal Roy  Hebrok Matthias 

PROVIDER: E-GEOD-52332 | ArrayExpress | 2013-11-14

SECONDARY ACCESSION(S): GSE52332SRP032968PRJNA227435

REPOSITORIES: GEO, ArrayExpress, ENA

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