Ontology highlight
ABSTRACT:
ORGANISM(S): Saccharomyces cerevisiae
SUBMITTER: Xuekui Zhang Zheng Kuang Benjamin P Tu Ling Cai Hongkai Ji Jef D Boeke
PROVIDER: E-GEOD-52339 | ArrayExpress | 2014-08-31
SECONDARY ACCESSION(S): SRP032970GSE52339PRJNA227448
REPOSITORIES: GEO, ArrayExpress, ENA
Nature structural & molecular biology 20140831 10
Under continuous, glucose-limited conditions, budding yeast exhibit robust metabolic cycles associated with major oscillations of gene expression. How such fluctuations are linked to changes in chromatin status is not well understood. Here we examine the correlated genome-wide transcription and chromatin states across the yeast metabolic cycle at unprecedented temporal resolution, revealing a 'just-in-time supply chain' by which components from specific cellular processes such as ribosome biogen ...[more]