Transcriptomics

Dataset Information

0

RNA-seq of the brain of Nothobranchius furzeri at different time points


ABSTRACT: Background: Comparison of temporal gene expression profiles (www.jenage.de) The RNA-seq data comprises 5 age groups: 5,12,20,27,39 weeks 25 samples: 5 biological replicates for each age group

ORGANISM(S): Nothobranchius furzeri  

SUBMITTER: Roberto Ripa   Matthias Platzer  Mario Baumgart  Reinhard Guthke  Eva T Tozzini  Steffen Priebe  Aurora Savino  Marco Groth  Alessandro Cellerino  Giovanna Testa  Michela Ori  Andreas Dix 

PROVIDER: E-GEOD-52462 | ArrayExpress | 2014-07-29

SECONDARY ACCESSION(S): GSE52462SRP033093PRJNA229052

REPOSITORIES: GEO, ArrayExpress, ENA

altmetric image

Publications

RNA-seq of the aging brain in the short-lived fish N. furzeri - conserved pathways and novel genes associated with neurogenesis.

Baumgart Mario M   Groth Marco M   Priebe Steffen S   Savino Aurora A   Testa Giovanna G   Dix Andreas A   Ripa Roberto R   Spallotta Francesco F   Gaetano Carlo C   Ori Michela M   Terzibasi Tozzini Eva E   Guthke Reinhard R   Platzer Matthias M   Cellerino Alessandro A  

Aging cell 20140725 6


The brains of teleost fish show extensive adult neurogenesis and neuronal regeneration. The patterns of gene regulation during fish brain aging are unknown. The short-lived teleost fish Nothobranchius furzeri shows markers of brain aging including reduced learning performances, gliosis, and reduced adult neurogenesis. We used RNA-seq to quantify genome-wide transcript regulation and sampled five different time points to characterize whole-genome transcript regulation during brain aging of N. fur  ...[more]

Similar Datasets

2015-02-06 | E-GEOD-63867 | ArrayExpress
2015-02-06 | E-GEOD-63923 | ArrayExpress
2013-03-29 | E-GEOD-45568 | ArrayExpress
2013-04-23 | E-GEOD-46257 | ArrayExpress
2015-02-06 | E-GEOD-63869 | ArrayExpress
2015-04-27 | E-GEOD-40997 | ArrayExpress
2015-02-06 | E-GEOD-63922 | ArrayExpress
2015-02-06 | E-GEOD-63925 | ArrayExpress
2016-07-22 | E-GEOD-80267 | ArrayExpress
2016-07-15 | E-GEOD-83618 | ArrayExpress