Transcriptomics,Genomics

Dataset Information

32

Large-scale characterization of DNA binding landscape of eukaryotic C2H2 zinc fingers


ABSTRACT: This SuperSeries is composed of the SubSeries listed below. Cys2-His2 zinc finger (C2H2-ZF) proteins represent the largest class of putative human transcription factors (TFs). However, it is unknown whether most C2H2-ZFs even bind DNA, or what sequences they bind. Using a combination of bacterial one-hybrid (B1H) assays, protein-binding microarrays (PBMs), and ChIP-seq, we have found that most natural C2H2-ZFs bind DNA both in vitro and in vivo. This SuperSeries contains the data for identification of C2H2-ZF binding preferences using these three approaches. Refer to individual Series

ORGANISM(S): synthetic construct  

SUBMITTER: Sanie Mnaimneh  Mihai Albu   Timothy R Hughes   Ernest Radovani   Jack Greenblatt   Hamed S Najafabadi   Ally Yang   Frank W Schmitges    

PROVIDER: E-GEOD-52523 | ArrayExpress| 2015-02-21

SECONDARY ACCESSION(S): GSE52523PRJNA229155

REPOSITORIES: GEO, ArrayExpress

altmetric image

Publications

Sorry, this publication's infomation has not been loaded in the Indexer, please go directly to PUBMED or Altmetric.

Similar Datasets

2015-02-21 | E-GEOD-52520 | ArrayExpress
2014-05-03 | E-GEOD-25723 | ArrayExpress
2014-05-02 | E-GEOD-31007 | ArrayExpress
2014-06-02 | E-GEOD-30992 | ArrayExpress
2014-06-02 | E-GEOD-42864 | ArrayExpress
2015-04-27 | E-GEOD-65719 | ArrayExpress
2014-08-09 | E-GEOD-53348 | ArrayExpress
2014-06-02 | E-GEOD-44338 | ArrayExpress
2012-03-27 | E-GEOD-11239 | ArrayExpress
| GSE52523 | GEO