Genomics

Dataset Information

237

HoxC11 ChIP-seq of LY2 Breast Cancer Cell Line


ABSTRACT: SRC-1 (NCOA1) is a steroid receptor coactivator that has been associated with various aspects of the progression of breast cancer disease such as tamoxifen resistance, metastasis, cell proliferation and invasiveness. In a tamoxifen resistant breast cancer cell line (LY2), SRC-1 has been found to interact with the developmental transcription factor HoxC11. ChIP-sequencing of HoxC11 in LY2 cells shows where the transcription factor binds throughout the genome. LY2 cells were treated with either tamoxifen or vehicle and immunoprecipitated with anti-Hoxc11

ORGANISM(S): Homo sapiens  

SUBMITTER: Leonie Young   Yuan Hao  Ailis Fagan 

PROVIDER: E-GEOD-54027 | ArrayExpress | 2014-01-14

SECONDARY ACCESSION(S): SRP035357GSE54027PRJNA234387

REPOSITORIES: GEO, ArrayExpress, ENA

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