Transcriptomics

Dataset Information

3

Calcineurin signaling regulates neural induction through antagonizing the BMP pathway


ABSTRACT: Calcineurin activity is required for neural differentiation of embryonic stem cells (ESC). We assessed gene expression changes at several time points of in vitro ESC to neural differentiation when calcineurin activity is inhibitied by its antagonist FK506 and Cyclosporin(CsA). d4, d6, d8, and d12 EBs of FK506/CsA treatment group (d3-8) and its non-treated control group were harvested from three independent experiments of in vitro differentiation of 46C mouse ESCs. Total RNA of each sample was extracted, reverse transcribed, labeled and hybridized to Affymetric Mouse Gene ST 1.0 Arrays.

ORGANISM(S): Mus musculus  

SUBMITTER: Ahryon Cho   Isabella A Graef 

PROVIDER: E-GEOD-54217 | ArrayExpress | 2014-04-01

SECONDARY ACCESSION(S): GSE54217PRJNA235950

REPOSITORIES: GEO, ArrayExpress

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