Ontology highlight
ABSTRACT:
OTHER RELATED OMICS DATASETS IN: PRJNA239358
ORGANISM(S): Danio rerio
SUBMITTER: Yujin Hoshida Vinitha Jacob Yelena Chernyavskaya Xintong Chen Poh Seng S Tan Kirsten C Sadler
PROVIDER: E-GEOD-55339 | ArrayExpress | 2015-02-09
SECONDARY ACCESSION(S): GSE55339PRJNA239358
REPOSITORIES: GEO, ArrayExpress
Action | DRS | |||
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E-GEOD-55339.idf.txt | Idf | |||
E-GEOD-55339.processed.1.zip | Processed | |||
E-GEOD-55339.raw.1.zip | Raw | |||
E-GEOD-55339.sdrf.txt | Txt |
Items per page: 1 - 4 of 4 |
Development (Cambridge, England) 20150106 3
UHRF1 (ubiquitin-like, containing PHD and RING finger domains, 1) recruits DNMT1 to hemimethylated DNA during replication and is essential for maintaining DNA methylation. uhrf1 mutant zebrafish have global DNA hypomethylation and display embryonic defects, including a small liver, and they die as larvae. We make the surprising finding that, despite their reduced organ size, uhrf1 mutants express high levels of genes controlling S-phase and have many more cells undergoing DNA replication, as mea ...[more]