Transcriptomics

Dataset Information

33

Deregulated Myc Requires MondoA for Metabolic Reprogramming and Tumorigenesis


ABSTRACT: In order to investigate the effect of MondoA loss on the expression of Myc-dependent genes, we performed a microarray analysis from RNAs isolated from TET21N cells expressing either control (siControl) or MondoA (siMondoA) siRNAs either with (NT) or without (Doxy) induced N-Myc expression. TET21N cells were grown in medium with either Doxy (Myc-Off) or No Treatment (Myc-On), then transiently transfected with either non-specific siRNA or MondoA siRNA in replicates. Cells were then lysed and RNA isolated.

ORGANISM(S): Homo sapiens  

SUBMITTER: Lisa McFerrin  Daniel Diolaiti   Robert Eisenman   Patrick Carroll    

PROVIDER: E-GEOD-55538 | ArrayExpress| 2015-01-20

SECONDARY ACCESSION(S): GSE55538PRJNA239925

REPOSITORIES: GEO, ArrayExpress

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