Transcriptomics

Dataset Information

4

Dissection of estrogen receptor alpha signaling pathways in osteoblasts using RNA-sequencing


ABSTRACT: The goal is to identify estrogen-dependent gene expression patterns using RNAseq for 3 different ERα forms in human osteoblasts. We analyzed 3 different forms of estrogen receptor alpha (ERα), 1) Wild-type, 2) NERKI (DNA-binding mutant) and 3) NOER (Nuclear Only ERα, not membrane). Each was infected into hFOB (human osteoblast) cells and treated with either vehicle or E2 (10nM) (n=3 for each group/treatment). RNAseq was then performed.

ORGANISM(S): Homo sapiens  

SUBMITTER: Sundeep Khosla   David G Monroe  David George Monroe 

PROVIDER: E-GEOD-55769 | ArrayExpress | 2015-03-11

SECONDARY ACCESSION(S): SRP039909GSE55769PRJNA240965

REPOSITORIES: GEO, ArrayExpress, ENA

Dataset's files

Source:
Action DRS
E-GEOD-55769.additional.1.zip Other
E-GEOD-55769.idf.txt Idf
E-GEOD-55769.sdrf.txt Txt
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