Transcriptomics

Dataset Information

299

Identification of genes associated with TGF-beta/Smad3-mediated renal inflammation and fibrosis by RNA sequencing


ABSTRACT: In this study, we employed high-throughput RNA sequencing (RNA-Seq) to identify the Smad3-dependent lncRNAs related to renal inflammation and fibrosis in Smad3 knockout (KO) mouse models of unilateral ureteral obstructive nephropathy (UUO) and immunologically-induced anti-glomerular basement membrane glomerulonephritis (anti-GBM GN). 12 kidney tissue samples of Smad3 KO/WT mice from normal control, UUO at day 5 or anti-GBM GN at day 10 models (n=2 in each group) for whole transcriptome RNA-sequencing.

ORGANISM(S): Mus musculus  

SUBMITTER: Qin ZHOU   Huiyao Lan  Qin Zhou 

PROVIDER: E-GEOD-55808 | ArrayExpress | 2014-03-26

SECONDARY ACCESSION(S): SRP040560GSE55808

REPOSITORIES: GEO, ArrayExpress, ENA

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