Ontology highlight
ABSTRACT:
ORGANISM(S): Homo sapiens
SUBMITTER: M Sanda M S Arredouani B Lu M. Simo Arredouani
PROVIDER: E-GEOD-55945 | ArrayExpress | 2014-03-18
SECONDARY ACCESSION(S): GSE55945PRJNA241405
REPOSITORIES: GEO, ArrayExpress
Arredouani Mohamed S MS Lu Bin B Bhasin Manoj M Eljanne Miriam M Yue Wen W Mosquera Juan-Miguel JM Bubley Glenn J GJ Li Vivian V Rubin Mark A MA Libermann Towia A TA Sanda Martin G MG
Clinical cancer research : an official journal of the American Association for Cancer Research 20090908 18
Identification of novel biomarkers and immunotherapy targets for prostate cancer (PCa) is crucial to better diagnosis and therapy. We sought to identify novel PCa tumor-associated antigens (TAA) that are expressed in PCa, absent in nonprostate human tissue, and immunogenic for immune responses restricted by human HLA.Using microarray analysis of normal and cancerous human prostate tissues, we identified 1,063 genes overexpressed in PCa. After validating 195 transcripts in publicly available arra ...[more]